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Synthetix Returns to Ethereum Mainnet as Falling Gas Fees Revive Onchain Perpetuals

By

Triparna Baishnab

Triparna Baishnab

Synthetix relaunches its perpetuals DEX on Ethereum mainnet after three years, signaling a shift back from L2s as gas fees collapse.

Synthetix Returns to Ethereum Mainnet as Falling Gas Fees Revive Onchain Perpetuals

Quick Take

Summary is AI generated, newsroom reviewed.

  • Synthetix relaunched its perpetuals DEX on Ethereum mainnet after three years

  • Ethereum’s liquidity dominance strengthens execution and pricing

  • Initial markets include BTC, ETH, and SOL with up to 50x leverage

  • The move signals renewed confidence in Ethereum as a DeFi hub

Synthetix makes a decisive move back to Ethereum mainnet after a three-year absence. The protocol relaunched its perpetuals trading platform in a private beta on December 17, 2025. High gas fees previously forced Synthetix and other derivatives platforms to migrate toward layer-2 networks like Base. Today, Ethereum’s fee environment has changed dramatically, reopening the door for complex, high-frequency DeFi activity on mainnet.

Collapsing Gas Fees Restore Mainnet Viability

Ethereum gas fees now sit at levels unimaginable during the last bull cycle. Transactions frequently clear below 5 gwei, reflecting a roughly 26x reduction from peak congestion periods. These conditions remove the primary barrier that pushed derivatives trading off mainnet. Traders can now execute perpetuals with predictable costs while benefiting from Ethereum’s deep liquidity and composability.

Liquidity Concentration Strengthens the Case for Mainnet

Ethereum still hosts more than 90% of onchain liquidity across DeFi. Synthetix capitalizes on this concentration by returning its perpetuals engine to where capital already resides. Fragmentation across multiple L2s diluted liquidity and increased complexity for advanced traders. Mainnet deployment simplifies execution, improves pricing, and reduces reliance on cross-chain bridges.

Perpetuals Relaunch Targets Core Markets First

Synthetix initially supports BTC, ETH, and SOL perpetual markets with leverage up to 50x. This focused rollout prioritizes the most liquid assets while stress-testing performance under real trading conditions. The team limits access through a private beta to ensure stability before broader expansion. This controlled approach reflects lessons learned from earlier scaling challenges.

Ethereum Reasserts Its Role as a DeFi Settlement Layer

Synthetix’s return sends a broader signal to the DeFi ecosystem. Ethereum no longer functions only as a settlement layer for rollups. Improved efficiency, proto-danksharding effects, and infrastructure upgrades restore its ability to host sophisticated financial primitives directly. Derivatives protocols may increasingly reassess whether L2-first strategies remain necessary.

References

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